Genetic Research Challenges

• Next-Generation Sequencing (NGS) and targeted enrichment cannot always resolve complex sequence regions

• Short NGS read lengths limit the ability to determine accurate sequence, map insertion points and detect structural variants and new alleles

• Typical target enrichment methods isolate only small fragments and cannot capture broader genomic context

Generation Biotech’s Solution

Multiplexed, magnetic particle-based isolation of genes and regulatory elements

• Large DNA segments (>20kb per oligo)
• Can identify unknown sequence space
• Productivity and resolution improvement combined with NGS

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• SNP-specific resolution of ambiguous allele combinations
• Associated mutation can be discovered and/or resolved
• Possible improvement of coverage for low-abundance SNPs

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